A summary of qualifications and background

Dr. Karen Hennessey is a board-certified infectious disease physician with over 25 years of clinical, academic, and leadership experience. She has served as Division Chief of Infectious Disease at Lincoln Hospital (NYC Health + Hospitals) since 1999, where she provides patient care, oversees infection control, directs quality improvement programs, and teaches fellows and residents. Her expertise in HIV care, infection control, sepsis, and hospital-acquired infections informs both her litigation support for defense counsel and her consulting services for healthcare organizations.

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Education & Training

  • Medical School: Wayne State University School of Medicine – Detroit, Michigan

  • Internship: Indiana University School of Medicine

  • Residency: NYU School of Medicine – Internal Medicine

  • Fellowship: NYU School of Medicine – Infectious Disease


Board Certification & Licensure

  • Board Certified in Internal Medicine

  • Board Certified in Infectious Disease

  • Licensed Physician – State of New York


Clinical & Leadership Roles

  • Division Chief, Infectious Disease – Lincoln Hospital / NYC Health + Hospitals (1999–Present)

  • Primary Care Physician for HIV-positive population

  • Inpatient consultant for infectious disease cases

  • Quality Improvement Coordinator

  • Teaching and supervision of fellows and residents


Past Leadership & Research Roles

  • Chair, Infection Control Committee

  • Site Investigator, Harlem AIDS Treatment Group – NIH/NIAID-funded TBTC (Tuberculosis Trials Consortium)

  • Principal Investigator, Pilot study for Directly Observed HIV Therapy – NYC AIDS Institute

  • Principal Investigator, Compassionate release programs for antiviral agents (Raltegravir, Tecovirimat – BRANY IRB oversight)


Academic & Teaching Appointments

  • Assistant Professor of Medicine – Weill Cornell University School of Medicine


Selected Publications

Representative peer-reviewed publications reflecting expertise in infectious disease, infection control, and hospital safety:

  • “A case of apparent ART-associated immune reconstitution inflammatory syndrome in Strongyloides infection.” Open Forum Infectious Diseases, 2023

  • “Bloodstream infections in hospitalized patients before and during the COVID-19 surge.” Antimicrobial Resistance & Infection Control, 2022

  • “HIV diagnosis and the Clinical Course of COVID-19 in New York City hospitals.” Journal of Infectious Diseases, 2021

  • “Hospital response to the Bronx Legionnaires’ Disease outbreak.” American Journal of Public Health, 2020

  • “Systematic review on vancomycin dosage for Clostridioides difficile infection.” Clinical Infectious Diseases, 2019

  • “Successful prevention of a multidrug-resistant hospital outbreak by pre-emptive infection control.” Infection Control & Hospital Epidemiology, 2015

  • “Treatment outcomes in hospitalized patients with Clostridium difficile infection: impact of guideline adherence.” Journal of Hospital Medicine, 2014

  • “Directly observed therapy to improve adherence in HIV-infected patients: pilot program outcomes.” AIDS Patient Care and STDs, 2012

  • “Nosocomial transmission and prevention of influenza and other respiratory infections in hospital settings.” Infection Control & Hospital Epidemiology, 2011

  • “Emerging resistance in Clostridium difficile: clinical challenges and infection control implications.” Clinical Microbiology and Infection, 2010

  • “Adherence to antiretroviral therapy in an urban HIV clinic: strategies and barriers.” Journal of Acquired Immune Deficiency Syndromes (JAIDS), 2008

  • “Sepsis protocol compliance and patient outcomes in a community hospital setting.” Journal of Critical Care, 2007

A complete bibliography is available in the full CV.


Professional Associations

  • Christian Medical and Dental Association (CMDA)

  • Infectious Diseases Society of America (IDSA)

  • Society for Healthcare Epidemiology of America (SHEA)

  • American College of Physicians (ACP)


Full CV

Attorneys and hospital administrators may request Dr. Hennessey’s complete CV for a detailed list of publications, research, and professional activities.

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